Panadol Extend

Provides immediate release and pain relief up to 8 hours.

With a patented bi-layer technology that allows for fast yet sustained release of paracetamol for long lasting pain relief.

As effective as some prescription strength treatment

Paracetamol 4000 mg was as effective as celecoxib 200 mg in reducing the pain scores of patients (based on the individual and composite Western Ontario and McMaster Universities Osteoarthritis Index visual analogue scale 

In another study, 80% (33 of 41 patients) found Panadol Extend to be as effective as celecoxib.

Provides effective and long-lasting pain relief for up to 8 hours

In this open label study, Panadol Extend sustained release achieved significantly improved pain levels (based on Visual Analog Scale [VAS]) vs. standard paracetamol in patients with knee osteoarthritis. The improved pain levels experienced on Panadol Extend could potentially encourage treatment adherence.

May delay opioid use

The graph aboves shows the number of days the patients were on an analgesic (mild opioid, codeine combination, stronger opioid). The mean number of analgesic equivalent days in patients taking Panadol Extend vs. standard paracetamol with a codeine combination and stronger opioid was less.

Therefore, in this retrospective longitudinal cohort analysis in 74,114 patients prescribed paracetamol for osteoarthritis, patients prescribed Panadol Extend for osteoarthritis had significantly lower mean analgesic days and were less likely to progress to narcotic analgesics compared to those on standard paracetamol tablets.

(The analgesic equivalent days were calculated as dose strength x quantity x number of prescriptions/defined daily doses.)